Name | 21-hydroxyprogesterone 21-acetate |
Synonyms | acetate Decorten Decosteron Deoxycorticosterone Acetate Desoxycorticosterone Acetate DEOXYCORTICOSTERONE ACETATE(RG) 21-Acetoxypregn-4-en-3,20-dione 21-hydroxyprogesterone 21-acetate 3,20-dioxopregn-4-en-21-yl acetate Desoxycorticosterone Acetate (200 mg) 21-HYDROXYPROGESTERONE 21-ACETATE VETRAN 21-Hydroxypregn-4-ene-3,20-dione Acetate (8xi,9xi,14xi)-3,20-dioxopregn-4-en-21-yl acetate 11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate |
CAS | 56-47-3 |
EINECS | 200-275-9 |
InChI | InChI=1/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17?,18?,19?,20-,22+,23+/m1/s1 |
Molecular Formula | C23H32O4 |
Molar Mass | 372.5 |
Density | 1.0415 (rough estimate) |
Melting Point | 157°C |
Boling Point | 421.94°C (rough estimate) |
Specific Rotation(α) | D20 +168 to +176° (dioxane) |
Flash Point | 218°C |
Water Solubility | 4mg/L(25 ºC) |
Solubility | This product is soluble in chloroform (1:1.5), acetone (1:30), ethanol (1:50), slightly soluble in ether (1:170), almost insoluble in water. |
Vapor Presure | 2.74E-10mmHg at 25°C |
Appearance | White solid |
Color | White to Off-White |
Merck | 2901 |
BRN | 2570798 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 175 ° (C=1, Dioxane) |
MDL | MFCD00003660 |
Physical and Chemical Properties | White crystalline powder, odorless, tasteless. Stable in air. Mp158-161 ℃; Specific rotation [α]20D +168 °-+176 ° (dioxane), +179 °-+184 °(1%, ethanol); ethanol solution has the maximum absorption at the wavelength of 240nm. This product is soluble in chloroform (1:1.5), acetone (1:30), ethanol (1:50), slightly soluble in ether (1:170), almost insoluble in water. |
In vivo study | Deoxycorticosterone acetate (DOCA) is an agent commonly used to induce hypertension in test animals. This form of hypertension relies on a central pressor mechanism, including altered regulation of the brain renin-angiotensin system. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
UN IDs | UN 2811 |
WGK Germany | 3 |
RTECS | HG0525000 |
HS Code | 2937290000 |
Hazard Class | IRRITANT |